THE ROLE OF STEM CELLS IN THE REGENERATION OF THE LIVER AND KIDNEYS

 Yushkov B.G., Danilova I.G., Kazakova I.A.

The general pathology and pathological physiology

Abstract.

This study shows that in response to liver damage observed activation of proliferation CD45lowCD117+ stem cells in the bone marrow and regenerating liver. In partial nephrectomy observed migration CD45lowCD117+ stem cells from bone marrow to the injured and the contrlateral kidney. These processes are accompanied by intense accumulation of macrophages in the stroma of regenerating organs.

Key words:

partial hepatectomy, partial nephrectomy, stem cells, macrophage.

Authors:

Yushkov Boris G.

Danilova Irina G.

Kazakova Irina A.

Institute of Medical Cell Technologies, Yekaterinburg

Institute of Immunology and Physiology of the Ural Branch of the Russian Academy of Sciences, Yekaterinburg

Yekaterinburg, Pervomayskaya, 106