RESULTS OF REFERENCE-LABORATORY WORK ON NER2 NEU-TESTING OF BREAST CARCINOMA IN SVERDLOVSK REGION FOR 2011
Sazonov S.V., Leontiev S.L., Brilliant A.A.
Technique
Abstract.
The purpose of research was definition of reference (revision) results spent in 2011 of the basic molecular-biological characteristics of tumoral cells of cancer breast for definition of indications to purpose of chemotherapy to patients from different establishments of public health services Sverdlovsk region. Necessity of reference-laboratory is proved, basic results HER2 neu testing in basics ummunohistochemistry laboratories are shown. The basic problems arising during performance of researches in ummunohistochemistry laboratories are designated, and as in the further at carrying out of repeated testing in reference-laboratory. The role of molecular-genetic research with application of a FISH-method is certain.
Key words:
breast carcinoma, HER2 neu testing, ummunohistochemistry, the FISH-analysis, reference-researches.