Сorrection of Histomorphometric Properties of Immunopoiesis Organs of Alloxan Diabetic Rats by Modulating of Macrophage Activity

Immunology, microbiology, genetics

Medvedeva S.J., Bulavintseva T.S., Danilova I.G.,

Gette I.F., Yushkov B.G., Lomaeva S.V., Abidov M.T.

Abstract.
Destructive changes, weight and cellularity of the thymus and spleen decrease, an increase in cells of lymphoid series in the bone marrow 30 days after the alloxan model of diabetes and the normalization of most of the studied parameters after the action of the 5-aminoftalhydrazide were revealed. Directional effects on macrophages promotes the restoration of structural changes and morphometric characteristics caused by alloxan diabetes in organs of the immunopoiesis.

Key words:
alloxan diabetes, 5-aminoftalhydrazide, macrophages, thymus, spleen, bone marrow.

Аuthors:
Medvedeva Svetlana Yu.
Bulavintseva Tatyana S. 
e-mail omella@yandex.ru
Danilova Irina G. 
e-mail ig-danilova@yandex.ru
Gette Irina F. 
e-mail i.goette@yandex.ru
Yushkov Boris G.
e-mail b.jushkov@ iip.uran.ru
Lomaeva Svetlana V. 
e-mail prothome@yandex.ru
Abidov Musa T. 
e-mail alina144@mail.ru