Results of Referencelaboratory Work on NER2 NEU-Testing of Breast Carcinoma in URFR for 2010

Public Health and the Public Health Services Organisation

Sazonov S.V., Leontiev S.L., Brilliant A.A.

Abstract.

The purpose of research was definition of reference (revision) results spent in 2010 of the basic molecular-biological characteristics of tumoral cells of cancer breast for definition of indications to purpose of chemotherapy to patients from different establishments of public health services URFR. Necessity of reference-laboratory is proved, basic results HER2 neu testing in basics ummunohistochemistry laboratories of URFR are shown. The basic problems arising during performance of researches in ummunohistochemistry laboratories are designated, and as in the further at carrying out of repeated testing in reference-laboratory. The role of molecular-genetic research with application of a FISH-method is certain.

Key words:

breast carcinoma, HER2 neu testing, ummunohistochemistry, the FISH-analysis, reference-researches.

Autors:

Sazonov Sergey V.

e-mail: Prof-SSazonov@yandex.ru

GBOU HPE Ural State Medical Academy of Health Ministry of Russia, Ekaterinburg

Russia, 620028, Ekaterinburg, ul. Repin, 3

Leontev Sergey L.

GBUZ

SO Center providing specialized types of medical care, “Institute for Medical Cell Technologies”, Ekaterinburg

Russia, 620036, Ekaterinburg, ul. Soboleva, 25

Brilliant Aleksandr A.

e-mail: alex-brilliant@mail.ru

GBUZ SO Center providing specialized types of medical care, “Institute for Medical Cell Technologies”, Ekaterinburg

Russia, 620036, Ekaterinburg, ul. Soboleva, 25