Gender-Specific Adaptation of Regulatory Mechanisms of Myocardial Contractility to External Load

The general pathology and pathological physiology

Balakin А.А., Kuznetsov D.А., Lisin R.V., Mukhlynina Е.А., Protsenko Yu.L.

Abstract.
The significant gender-specific differences in morphological features and biomechanical performances of contractility («force-length» and «force-velocity» relations) were found in healthy and hypertrophied myocardium of Wistar rats. The differences build up during the adaptation of myocardial contractility to the external loads.

Key words:
rat myocardium, hypertrophy, gender-specific differences, force-length and force-velocity relations.

Authors:

Balakin Аlexandr А.
Kuznetsov Daniil A.
Lisin Ruslan V.
Mukhlynina Еlena А.
Protsenko Yuri L.

Institute of Immunology and Physiology, UB of RAS
Russia, Ekaterinburg, Pervomayskaya str., 106
e-mail: y.protsenko@iip.uran.ru