Clinical Manifestations and Optimized Treatment of Cytomegalovirus Hepatitis in Infants

Clinical experience

Ushakova R.A., Kovtun O.P., Sheina O.P., Pustynnikova S.V.

Abstract.

43 first life year children with CMV-hepatitis were observed. The clinical research program and treatment protocol were approved by the local ethics committee. Parental informed consent was obtained in all the stages of examination and patient-specific therapy. During the treatment 37 patients showed significant improvement of AST, ALT, and alkaline phosphatase levels back to normal ranges and were confirmed to reduce their liver and spleen size.

Key words:

children, cytomegalovirus hepatitis, antiviral therapy.

Authors: 

Ushakova Rima A.

e-mail: nikolay_ushakov@olympus.ru;
Ural State Medical University Russian Ministry of Health, Candidate of Medical Science, Associate Professor of Department of Pediatrics and Neonatology, Advanced Training Faculty Professional Retraining; State budget Educational Institution of Higher Vocational Education
3, Repina st., Yekaterinburg, Russia

Kovtun Olga P.

e-mail: kovtun@usma.ru;
Ural State Medical University Russian Ministry of Health; MD, Professor, Head of department of Pediatrics and Neonatology, Advanced Training Faculty Professional Retraining; State Budget Educational Institution of Higher Vocational Education
3, Repina st., Yekaterinburg, Russia

Sheina Olga P. 
Municipal Autonomous Institution Children's City Hospital №9, Yekaterinburg;
Candidate of Medical Science, Deputy Chief Doctor in Clinical Care
51, Reshetskaya st. Yekaterinburg, Russia

Pustynnikova Svetlana V.
Municipal Autonomous Institution Children's City Hospital №9, Yekaterinburg;
Candidate of Medical Science, Deputy Chief Doctor in Ambulatory Care;
51, Reshetskaya st. Yekaterinburg, Russia