The Influence of Adrenaline on Lipid Peroxidation in Myelokaryocytes of Adult and Old Rats In Vitro

The general pathology and pathological physiology

Shcherbakov D.L., Yemelyanov V.V., Meshchaninov V.N.

Abstract.

A decrease of intensity of lipid peroxidation (LPO) in myelokaryocytes of rats with age was found. In vitro adrenaline caused an increase in the intensity of lipid peroxidation in myelokaryocytes of mature and old rats. Activation of LPO under the influence of adrenaline in myelokaryocytes of old rats was more intensive. It is recommended when working with cell cultures, to carry out pre-processing with antioxidant to prevent destruction through LPO-processes, especially of older organisms.

Key words:

myelokaryocytes, adrenaline, lipid peroxidation.

Authors:

Scherbakov Denis L.
e-mail: cdcom2@yandex.ru
Ural state medicine academy; Institute of medical cell technologies
620000, Yekaterinburg, Russia, Soboleva, 25

Yemelyanov Viktor V. e-mail: evvd@list.ru
Ural Federal University named after B.N.Yeltsin, Yekaterinburg, Russia.
620002, Yekaterinburg, Russia, Mira, 19–3

Meshchaninov Victor N. e-mail: mv-02@yandex.ru
Institute of medical cell technologies, Ural state medicine academy,
620000, Yekaterinburg, Russia, Soboleva, 25