Thestudyofneonatal Survival Ofinfantswithmultipleorganfailure by Kaplan-Meier Product- Limit Analysis

Technique

Minochkin P.I., Volosnikov D.K., Prosekov V.A., Pankratov A.O., Lapin O.V.,

Suvorov G.N., Rusakov V.E., Poniatov A.G., Taksheev N.N., Shabalin A.A.

Abstract.

The study of survival of newborn infants with multiple organ failure (MOF) showed that mortality up to the one year of life in this group was 29.1% and survivalamounted to 70.9%.The probability of survival up to the one year of life in newborns with MOF was 0.71. The highest survival rate observed among term infants with MOF with a gestational age of 37–41 weeks, and also in preterm infants with gestational age of 28–32 weeks, the probability of survival up to the one year of life in infants of these group was 0.75. In preterm infants with gestational age 33–36 weeks, the probability of survival up to one year of life amounted to 0.6. And lowest survival rate observed in extremely premature infants with MOF, with gestational age 26–27 weeks, the probability of survival to the one year of life they amounted to 0.57. The greatest risk of fatal outcomes observed at the beginning of the disease in the first 2 months of life. The relative risk of death among children under one year of life with MOF amounted to 0.72 with a significance level р<0.0001.

Key words:

multiple organ failure, newborn baby, survival.

Authors:

Minochkin Pavel I.
Chelyabinsk State Medical Academy, Russia
pavelmin@mail.ru

Volosnikov Dmitry K. 
Chelyabinsk State Medical Academy, Russia
pavelmin@mail.ru

Prosekov Vladimir A.
Regionalchildren’sclinicalhospital, Chelyabinsk, Russia
pavelmin@mail.ru

Pankratov Alexey O.
Regionalchildren’sclinicalhospital, Chelyabinsk, Russia
pavelmin@mail.ru

Lapin Oleg V. 
Regionalchildren’sclinicalhospital, Chelyabinsk, Russia
pavelmin@mail.ru

Suvorov Georgy N.
Regionalchildren’sclinicalhospital, Chelyabinsk, Russia
pavelmin@mail.ru

Rusakov Vladimir E.
Regionalchildren’sclinicalhospital, Chelyabinsk, Russia
pavelmin@mail.ru

Poniatov Albert G.
Regional children’s clinical hospital, Chelyabinsk, Russia
pavelmin@mail.ru

Taksheev Nikolai N
Regional children’s clinical hospital, Chelyabinsk, Russia
pavelmin@mail.ru

Shabalin Alexey A
Regionalchildren’sclinicalhospital, Chelyabinsk, Russia
pavelmin@mail.ru

454092, Department of hospital pediatrics, clinical immunology andallergology, Chelyabinsk State Medical Academy, Vorovskogo str. 64, Chelyabinsk city, Russia

454092, Intensive Care Unit, Regional children’s clinical hospital, 42A, Bluhera str., Chelyabinsk city, Russia