Results of Studying Post-Vaccination Immunity in Under-3-Year-Olds Vaccinated with Tbe-Encepur Children

Immunology, microbiology, genetics

Ankudinova A.V., Romanenko V.V., Kovtun O.P., Kilyachina A.S., Averyanov O.Yu., Esyunina M.S., Shelkova E.S.

Abstract.

At present immunization is the main action in prevention of tick-borne encephalitis both in adults and children. Yet, no studies of post-vaccination immunity in children under 3 years of age vaccinated against TBE in pediatric doses have been conducted so far. In order to evaluate immunological efficacy and the intensity of post-vaccination immunity as well as safety of the Encepur Children vaccine we conducted a study of this vaccine in children from 15 months to 3 years of age. The study results showed that the TBE-Encepur Children vaccine is safe for children from 15 months and the whole immunization schedule (2 vaccinations and 1 revaccination) ensures their reliable protection against tick-borne encephalitis.

Key words:

tick-borne encephalitis, children from 15 months to 3 years of age, Encepur Children, post-vaccination immunity.

Authors:

Ankudinova A.V. 
e-mail: Ankudinova_AV@66.rospotrebnadzor.ru
Epidemiologist of the Center for Hygiene and Epidemiology in the Sverdlovsk Region, Federal Budget-Funded Institution of Public Health, Ekaterinburg

Romanenko V.V. 
Doctor of Medical Sciences, Deputy Head Doctor of the Center for Hygiene and Epidemiology in the Sverdlovsk Region, Federal Budget-funded Institution of Public Health, Ekaterinburg

Kovtun O.P. 
Doctor of Medical Sciences, Professor, Provost of the Ural State Medical Academy of the Russian Ministry of Health and Social Development, Ekaterinburg

Kilyachina A.S. 
Candidate of Medical Sciences, Virologist of the Laboratory for Control of Biological Factors of the Center for Hygiene and Epidemiology in the Sverdlovsk Region, Ekaterinburg

Averyanov O.Yu.
Head Doctor of Children’s Hospital №11, Ekaterinburg

Esyunina M.S. 
Expert of the Sverdlovsk Regional Rospotrebnadzor Agency, Ekaterinburg

Shelkova E.S. 
Candidate of Medical Sciences, Epidemiologist of Children’s Hospital №5, Ekaterinburg, Russia, 620078 Ekaterinburg, Otdelny lane 3