Preparation of Women with Background Endocrine Pathology for IVFCycles

Bachmakova N. V., Dubrovina O. S., Lisovskaya T. V., Mayasina E. N., Sentjurina L. B.

Ural Research Institute for Maternal and Child Welfare, Ekaterinburg, Russia;
Family Medicine Center, Ekaterinburg, Russia

Abstract.
Endocrine forms of female infertility are the most difficult to treat, including with the use of assisted reproductive technology (ART). Draws attention to the probable underestimation of the clinical symptoms of endocrine pathology background in handling women obstetrician-gynecologist for infertility, which makes the wrong choice programs superovulation. The aim of this work was to study the effect of different regimens of background endocrine pathology in patients with infertility on outcomes of treatment with ART. Material and methods. A comparative study of the effectiveness of ART cycles in women with endocrine form of infertility receive (320 pers.) and not receiving (470 pers.) correction of background hormonal and metabolic disorders during pregravidal training. Results and discussion. Adequate correction of hormonal and metabolic disorders during pregravidal training during the program of ART increases the number of pregnancies in patients with various endocrine disorders: from 22.7% to 40.2%, respectively, p<0.05.
Keywords:
endocrine form of infertility, pregravid preparation, assisted reproductive technologies.

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Authors
Bachmakova Nadezhda V., e-mail: uchsek@niiomm.ru
prof., MD., head of Ural Research Institute for Maternal and Child Welfare; Repina
street, 1, Ekaterinburg, 620028, Russian Federation

Dubrovina Oksana S., e-mail: osd40@mail.ru
part-time graduate, «Ural research Institute for Maternity and Child Welfare»;
endocrinologist, JSC «Center of family medicine»;
Repina street, 1, Ekaterinburg, 620028, Russian Federation

Lisovskaya Tatiana V., e-mail: tv.lis@mail.ru
MD, Deputy General Director on science, JSC «Center of family medicine», Division
commander
Vasilyev street 1/3, Ekaterinburg, 620102, Russian Federation;
leading researcher, «Ural research Institute for Maternity and Child Welfare»»,
Repina street, 1, Ekaterinburg, 620028, Russian Federation

Mayasina Elena N., e-mail: senturinal@mail.ru
Obstetrician-gynecologist, head of IVF Department №1, JSC «Center of family
medicinе», Division commander Vasilyev street 1/3, Ekaterinburg, 620102, Russian
Federation, e-mail: elena.mayasina@gmail.com
Sentjurina Lidiya B.
PhD, endocrinologist, JSC «Center of family medicine», Division commander Vasilyev
street 1/3, Ekaterinburg, 620102, Russian Federation