The Features of Amino Acid Content in the Hematopoietic Tissue in Conditions of Aseptic Inflammation

Bykova M.Ju., Miheeva I.V.

Institute of Immunology and Physiology of the Ural Branch of the Russian Academy of Sciences; Ural Federal University named after the First President of Russia B.N. Yeltsin, Yekaterinburg, Russian Federation

Abstract.

Activation of granulocytopoiesis in the bone marrow is accompanied by quantitative shifts in the amino acid composition of blood, ECM, myelokaryocytes and erythrocytes. The total amount of free amino acids retained within myelokaryocytes normal but their concentration decreases in the extracellular matrix (in particular amino groups of α-ketoglutarate, acetyl-CoA, and nonessential, glycogenic, ketogenic amino acids).

Keywords:

extracellular matrix, hematopoiesis, amino acid

REFERENCES
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2. Grebenjuk O.A. Condition of amino acid metabolism of hematopoietic tissue in conditions which have extreme effects on the body: avtoref… kand. biol. nauk / UGMA. Ekaterinburg, 1997. 24 р.
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Authors
Bykova Marija Ju., mr_bykova@mail.ru
Institute of Immunology and Physiology of the Ural Branch of the Russian Academy of Sciences Junior Researcher
Russian Federation, 620049, Yekaterinburg, ul. Pervomajskaja, 106
Ural Federal University named after the First President of Russia B.N. Yeltsin
Research Assistant
Russian Federation, 620002, Yekaterinburg, ul. Mira, 19

Miheeva Irina V., tishina_666@bk.ru
Ural Federal University named after the First President of Russia B.N. Yeltsin
Student
Russian Federation, 620002, Yekaterinburg, ul. Mira, 19