Change of the Gemoglobin-Profile at Rats in the Conditions of Reparativny Regeneration the Liver

Brilliant S. A.

Institute of Medical Cellular Technologies; Institute of Immunology and Physiology of the Ural Branch of the Russian Academy of Sciences, Yekaterinburg, Russian Federation

Abstract.

Work is devoted to a question of change of proteinaceous fractions of hemoglobin in blood and marrow in the conditions of reparative regeneration a liver. It is shown that in a blood-groove cages of the small sizes which are more adapted for functioning at liver regeneration prevail. Level 5, 6 isoforms the hemoglobin increase of possessing the best of transfer oxygen properties, and decrease in level the 3 fraction of hemoglobin. At various physiological and pathological states change of a ratio of haemoglobins of different types is caused by activation or suppression of types of cages corresponding the eritroid that leads to ratio change between populations of erythrocytes in a blood-groove.

Keywords:

hemoglobin, marrow, erythrocytes, liver

REFERENCES
1. Dudarev V.P., Starodub N.F. O vlijanii gipo-, giperoksii na frakcionnyj sostav gemoglobina u krys. iziol. zhurn. 1979. 4. pp. 413-418
2. Kozinec G.I., Makarov V.A. Issledovanie sistemy krovi v klinicheskoj praktike.-M.: Triada-H. 1997. 480 p. 
3. Maurer G. Disk-jelektroforez. Teorija i praktika jelektroforeza v poliakrilamidnom gele. M: «Mir». 1971. 271 p.

Authors
Brilliant Svetlana A., e-mail: svetlana.brilliant@bk.ru
Institute of Immunology and Physiology of the Ural Branch of the Russian Academy of Sciences
junior researcher
Russian Federation, 620049, Yekaterinburg, Pervomayskaya st., building 106
Institute of Medical Cellular Technologies
researcher
Russian Federation, 620036, Yekaterinburg, Soboleva st., building 25