ADAPTIVE POSSIBILITY OF THE ORGANISM OF WOMEN WITH PHYSIOLOGICAL PREGNANCY AND EXTRACORPORAL FERTILIZATION
DOI: 10.22138/2500-0918-2020-17-2-121-130
J.S. Chehova, E.A. Kashuba, S.V. Solov'eva, M.V. Antonova
Tyumen State Medical University, Tyumen, Russian Federation
Abstract. The study of the restructuring of the body of a pregnant woman with relation to the theory of functional systems is necessary for a complete understanding of the formation of adaptive processes. Of particular interest is pregnancy resulting from extracorporeal fertilization (IVF). Aim. to estimate the adaptive capacity of women with physiological pregnancy and IVF. Materials and methods. The object of the study: healthy women before pregnancy and in the I trimester (I group), patients with tubal-peritoneal infertility at the planning stage and after an effective IVF (II group), women with an unsuccessful IVF (III group). We conducted a study of the functional state of the cardiovascular system of pregnant women with the calculation of adaptive potential (AP) by R. M. Bayevsky. We assessed the regulation of the vegetative nervous system — Kerdo index (KI). We determined the state of regulatory systems with the stress index (L.H. Garkavi et al.). Results. In patients with physiological pregnancy, we noted the effect on the cardiovascular system of the autonomic nervous system and the tension of adaptive reactions. In pregnant women with IVF we recorded the depletion of adaptive activity of the sympathetic autonomic nervous system. This led to a significant strain or failure of adaptation with the predominant influence of the parasympathetic autonomic nervous system. Conclusion. Significant differences in the studied parameters in women with ineffective IVF program at the stage of pregnancy planning may have important prognostic value for determining the tactics of management of patients.
Keywords: physiologically pregnancy, extracorporeal fertilization, adaptation, adaptive potential, vegetative regulation
Received 28.04.2020
For citation:
Chehova J.S., Kashuba E.A., Solov'eva S.V., Antonova M.V. Adaptive possibility of the organism of women with physiological pregnancy and extracorporal fertilization. Vestn. Ural. Med. Akad. Nauki. = Journal of Ural Medical Academic Science. 2020, Vol. 17, no. 2, pp. 121–130. DOI: 10.22138/2500-0918-2020-17-2-121-130 (In Russ)
REFERENCES
1. Sudakov K. V. Funkcional'nye sistemy [Functional system]. Moskow: RAMS, 2011 (in Russ).
2. Chyornaya E. E. Kojnosov A.P. Features of adaptation of the cardiovascular system of newcomer residents of the Middle Ob region during physiological pregnancy. Sovremennaya nauka: aktual'nye problemy teorii i praktiki. Seriya: Estestvennye i tekhnicheskie nauki [Scientific and practical journal]. 2017, No 12, pp. 25-29 (in Russ).
3. Mihajlova S. V., Kuzmichev YU. G., Krasnikova L. I., Hrycheva T. V., Saburcev S. A., Krylov V. N. et al. Physiological features of the adaptive reactions of the body. Zhurnal fundamental'noj mediciny i biologii [Journal of Fundamental Medicine and Biology]. 2018, No 3, pp. 24-38 (in Russ).
4. Vyalikova Yu. V. Alieva A.Ya., Najko Yu.V. Features of pregnancy and childbirth in patients after in vitro fertilization. Byulleten' medicinskih internet-konferenci [Bulletin of Medical Internet Conferences]. 2015, No 5(5), pp. 442-442 (in Russ).
5. Mizuno T., Tamakoshi K., Tanabe K. Anxiety during pregnancy and autonomic nervous system activity: a longitudinal observational and cross-sectional study. Journal of psychosomatic research. 2017, No. 99, pp.105-111.
6. Spicin A. P., Carev YU. K., Spicin A. A. The use of integral indices of central and peripheral hemodynamics for early diagnosis of changes in the cardiovascular system in young people. II Mezhdunarodnyj forum vrachej obshchej praktiki/semejnyh vrachej [II International Forum of General Practitioners], 2019, p.125-128.
7. Barylyak L. G., Malychkova R.V.,ТolstanovО.K., ТymochkoО.B. Comparative estimation of informativeness of leucocytary index of adaptation by Garkavi and by Popovych. Medical hydrology and rehabilitation, 2013, No 11(1), pp. 5-22 (in Russ).
8. Zeng Z. Liu F., Li S. Metabolic adaptations in pregnancy: a review. Annals of Nutrition and Metabolism, 2017, No 70(1), pp. 59-65.
9. Serov V.N., Suhih G.T., Prilepskaya V.N., Radzinskij V.E. Obstetrics and Gynecology Outpatient Care Guide. M.: GEOTAR-Media, 2017 (in Russ).
10. De Haas S. Physiological adaptation of maternal plasma volume during pregnancy: a systematic review and meta-analysis. Ultrasound in Obstetrics & Gynecology, 2017, No 49(2), pp. 177-187.
11. Kostenko I.V., Rogozhina I.E., Vedishchev E.S., Olenko E.S., Kirichuk V.V. et al. The functional state of the body and its adaptive capacity in pregnant women with gestosis. Vestnik Tambovskogo universiteta. Seriya: Estestvennye i tekhnicheskie nauki [Tambov University Reports. Series Natural and Technical Sciences], 2012, No.17(5), pp. 1452-1455 (in Russ).
12. Tajtubaeva G.K., Gribacheva I.A. Changes in the autonomic nervous system during pregnancy. Ural'skij medicinskij zhurnal [Ural Medical Journal], 2019, No 5, pp. 67-72 (in Russ).
13. Boeldt D.S., Bird I.M. Vascular adaptation in pregnancy and endothelial dysfunction in preeclampsia. The Journal of endocrinology, 2017, No 232(1), pp. 27-44.
14. Athani K.B., Kalyanshetti S.B. A comparative study of cardiovascular autonomic function tests between pregnant and non-pregnant women. International Journal of Physiology, 2018, No 6(4), pp. 11-17.
Authors
Yulia S. Chekhova
Assistant of the Department of Infectious Diseases with a course of children's infections
doktor-ch@bk.ru
Svetlana V. Solovieva
Doctor of Medical Sciences, Professor, Head of the Department of Biology
svsolov@mail.ru
Eduard A. Kashuba
Doctor of Medical Sciences, Professor, Head of the Department of Infectious Diseases with a course of children's infections
kashuba.ed@mail.com
Maria V. Antonova
Postgraduate student of the Department of Infectious Diseases with a course of childhood infections
antonovamariav@mail.ru
Tyumen State Medical University of the Ministry of Health of the Russian Federation, Tyumen
54, Odesskaya str., Tyumen, 625023, Russian Federation