CYTOLOGICAL CHARACTERISTICS OF THE PROLIFERATION AND APOPTOSIS PROCESSES ON BUCCAL EPITHELIUM IN CHRONIC GINGIVITIS

DOI: 10.22138/2500-0918-2019-16-1-22-26

V.V. Bazarnyi, L.G. Polushina, A.Yu. Maksimova, E.N. Svetlakova, E.A. Sementsova

Ural State Medical University, Yekaterinburg, Russian Federation

Abstract. The aim of this work is to estimation of buccal cytology in chronic gingivitis.
Materials and methods. 22 patients with chronic gingivitis (CG) and 20 healthy volunteers were examined. The buccal cytology was examined before treatment. When counting 1000 cells basal and differentiated cells, the apoptotic index and the cytogenetic index were determined.
Results. The level of epithelial cells in basal layer tended to decrease, while the content of binuclear cells of the intermediate and superficial layers decreased by 34% in comparison with the control group (p=0.02). The apoptotic index and the cytogenetic index did not change significantly. Conclusion. The study revealed features of the oral cavity tissue homeostasis in chronic gingivitis. An insignificant contravention of epithelial cells proliferation processes was established when apoptosis did not change. Comparing these data with previously studied cytological changes in the buccal epithelium in chronic generalized periodontitis, one can formulate the mechanisms of the of periodontal pathology progression.

Keywords: buccal cytology, chronic gingivitis, apoptosis

There is no conflict of interest.

Contact details of the corresponding author:
Vladimir V. Bazarnyi
vlad-bazarny@yandex.ru

Received 05.03.2019

For citation:
Bazarnyi V.V., Polushina L.G., Maksimova A.Yu., Svetlakova E.N., Sementsova E.A. Cytological characteristics of the proliferation and apoptosis processes on buccal epithelium in chronic gingivitis. Vestn. Ural. Med. Akad. Nauki. = Journal of Ural Medical Academic Science. 2019, Vol. 16, no. 1, pp. 22–26. DOI: 10.22138/2500-0918-2019-16-1-22-26 (In Russ)

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Authors
Vladimir V. Bazarnyi
Dr. Sci. (Med.), Professor of the Department of Clinical Laboratory Diagnostics and Bacteriology
vlad-bazarny@yandex.ru

Larisa G. Polushina
Researcher
polushina-larisa@bk.ru

Arina Y. Maksimova
junior researcher
oreshek92@list.ru

Svetlakova Elena N.
Cand. Sci. (Med.), Assistant Professor of the Preclinical Dentistry Department and Physiotherapy of Dental diseases
svet_anel11@mail.ru

Sementsova Elena A. 
Cand. Sci. (Med.), Assistant of the Preclinical Dentistry Department and Physiotherapy of Dental Diseases
vanevs@mail.ru

Ural State Medical University
Russian Federation, 620028, Ekaterinburg, Repin str. 3

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)