DIMENSIONAL DETERMINANTS IN IMPROVING DEBUT OUTCOMES IN SCHIZOPHNIA: A PERSONALITY-ORIENTED APPROACH

DOI: 10.22138/2500-0918-2025-22-3-303-315

V.A. Chinarev ¹,², E.V. Malinina¹

¹South Ural State Medical University, Chelyabinsk, Russian Federation;
²GBUZ Regional Clinical Specialized Neuropsychiatric Hospital No. 1, Chelyabinsk,
Russian Federation

Abstract. A comprehensive analysis of clinical, socio-demographic and psychological factors that determine functional recovery, quality of life and the course of the disease in patients with manifestations of schizophrenic spectrum disorders act as key determinants that influence the individual characteristics of the course of the disease and the adaptive capabilities of patients. Establishing relationships between these parameters helps to improve the prognosis and improve the quality of medical care provided to this category of patients. The goal of the research was to investigate the complex effects of clinical and psychosocial factors on improving outcomes after the first psychotic episode in individuals with schizophrenia, as well as to assess the effectiveness of a personalized approach to functional recovery and improvement in quality of life for these patients. Materials and methods: The study was conducted using data from 109 individuals who received treatment for the first psychotic episode at the Department of GBUZ «OKSPNB No. 1» in Chelyabinsk. The comprehensive approach included a clinical and psychopathological assessment, the use of standard psychometric scales, and semi-structured interviews to determine the degree of personal recovery using the CHIME model. Results and discussion: The main results of the study indicate that predictors of a positive outcome include social support, active involvement in treatment planning, restoration of productivity, and formation of a positive self-perception. Social integration and availability of life plans are important for accelerating recovery, while lack of critical attitude and social isolation are associated with unfavorable outcomes. Conclusion: A personalized approach that combines social, psychological, and functional aspects emphasizes the need to move beyond the biomedical model in treating the onset of schizophrenia, transforming recovery into a process of identity reconstruction through interdisciplinary collaboration.

Keywords: personalized approach, first episode of psychosis, dimensional approach, onset of schizophrenia

There is no conflict of interest.
Contact details of the corresponding author:
Vitaly A. Chinarev
va.chinarev@bk.ru
Recieved 05.03.2025
For citation: Chinarev V.A., Malinina E.V. Dimensional determinants in improving debut outcomes in schizophrenia: a personality-oriented approach. [Online] Vestn. Ural. Med. Akad. Nauki. = Journal of Ural Medical Academic Science. 2025, Vol. 22, no. 3, pp. 303–315. DOI: 10.22138/2500-0918-2025-22-3-303-315 (In Russ)

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Authors:
Vitaly A. Chinarev
GBUZ «Regional Clinical Specialized Neuropsychiatric Hospital No. 1» 
Head of the men's clinical department of the first psychotic episode, psychiatrist
South Ural State Medical University of the Ministry of Health of the Russian Federation
Assistant Professor of the Department of Psychiatry
va.chinarev@bk.ru
ORCID: 0000-0003-3471-5293
Chelyabinsk, Russian Federation

Elena V. Malinina
South Ural State Medical University of the Ministry of Health of the Russian Federation
Doctor of Medical Sciences, Professor, Head of the Department of Psychiatry
malinina.e@rambler.ru
Chelyabinsk, Russian Federation