Long-term functions of pancreas after treatment of severe acute pancreatitis
Omelyanovich D. A., Blagovestnov, D. A., Andreev V. G., Almakaev F. I.
Russian medical Academy of postgraduate education,
Moscow, Russian Federation
Abstract.
Introduction. The aim of this work is to evaluate the long-term functions of pancreas of the patients after a different treatment and tactical approaches to the treatment of severe acute pancreatitis. Materials and methods. Long-term functions of pancreas were studied in 210 patients undergoing severe acute pancreatitis in the period from 2003 to 2013. 80 patients of 210 were examined in hospital. Results. Diabetes developed in 62 (29.5 %) patients, of which insulin – 30 (14.3 %) patients. Exocrine dysfunction was diagnosed in 116 (55.2 %) patients. Enzyms insufficiency of the pancreas developed in 35 % examined patients. Conclusions. Exocrine dysfunction, enzyms insufficiency of the pancreas, diabetes develops most often in patients undergoing pancreonecrosis involving pancreatic parenchyma more than 30 % of the area of the pancreas.
Key words:
functions of pancreas, acute pancreatitis
REFERENSES
1. Ermolov, A.S. Diagnostika i lechenie ostrogo pankreatita. A.S. Ermolov, P.A. Ivanov, D.A. Blagovestnov, A.V. Grishin, V.G. Andreev. – M.: Vidar, 2013 — 382 p.
2. Beger, H.G. Severe acute pancreatitis: Clinical course and management. H.G. Beger, B.M. Rau. World J. Gastroenterol. – 2007 – 13 – P. 5043-5051
3. Nesterenko, Ju.A. Diagnostika i lechenie destruktivnogo pankreatita. Ju.A. Nesterenko,V.V. Laptev, S.V. Mihajlusov. — M.: OOO “Binom-press”, 2004 – 304 p.
4. Dibirov, M.D. Pankreonekroz. Protokol diagnostiki i lechenija. Uchebno-metodicheskoe posobie. M.D. Dibirov, A.A. Juanov. – Moskva, 2012 — 366 p.
5. Shapoval'janc, S.G., Operativnye vmeshatel'stva pri ostrom destruktivnom pankreatite. S.G. Shapoval'janc, A.G. Myl'nikov, A.G. Pan'kov. Annaly hirurgicheskoj gepatologii. — 2010 – No. 2 — p. 58
6. IAP/APA evidence-based guidelines for the management of acute pancreatitis. Working Group IAP/APA (International Association of Pancreatology. American Pancreatic Association) Acute Pancreatitis Guidelines. Pancreatology. — 2013- No. 13- Р. 1- 15.
7. Bagnenko, S.F. Ostryj pankreatit (Protokoly diagnostiki i lechenie). S.F. Bagnenko, A.D. Tolstoj., V.B. Krasnogorov i dr. Annaly hirurgicheskoj gepatologii. – 2006. — Vol. 11 – No. 1 — pp. 60–66
8. Savel'ev, B.C. Pankreonekrozy / V.S. Savel'ev, M.I. Filimonov, S.Z. Burnevich. — M.: MIA, 2008 – 264 c.
9. Burnevich, S.Z. Prognozy i ishody hirurgicheskogo lechenija bol'nyh pankreonekrozom v svete sovremennyh predstavlenij o tanatogeneze zabolevanija (soobshhenie 1 i 2) / S.Z. Burnevich, Ju.N. Ignatenko, K.V. Kirsanov. Annaly hirurgii. — 2004. – No. 3,4. — p. 30-32 i 37-41.
10. Atilla, S. Outcome and quality of life of patients with acute pancreatitis requiring intensive care. S. Atilla,C. Lakshmipath., K.W.Lee Kenneth, A. Samuel, Tisherman. J. Surg. Res. — 2000. — 91 pp. 89-94.
Authors
Omelyanovich Dmitriy A.
postgraduate student of the Department of Emergency and General surgery chair of Russian medical Academy of postgraduate education.
o.d.a@mail.ru
Blagovestnik Dmitry A.
MD, Dean of the surgical faculty, Professor, Department of emergency and General surgery chair
Andreev Vadim G.
MD associate Professor Department of emergency and General surgery chair
Almakaev Felix R.
senior laboratory assistant of the Department of emergency and General surgery chair