Immunometabolic Interrelations in Apparently Healthy Residents Arkhangelsk
Dobrodeeva L.K., Zubatkina I.S., Samodova A.V., Zubatkina O.V., Malachova M.Ya., Popov A.A.
Institute of Environmental Physiology, Ural Branch of the Russian Academy of Sciences, Arkhangelsk, Russian Federation;
Northern State Medical University, Archangelsk,
Russian Federation;
International Institute of the Biological Systems,
Saint-Petersburg, Russian Federation;
North-Western State Medical University named
after I.I. Mechnikov, Saint-Petersburg, Russian Federation
Abstract. A comprehensive survey of 49 healthy volunteers with the definition of a series of biochemical and immunological parameters. It is established that the reduction of pyruvate in the peripheral blood on the background of increasing the activity of anaerobic metabolism associated with a reduction of the content and increased phagocytosis of activated immune cells, cytotoxic T lymphocytes and natural killer.
Keywords: lactate, piruvate, transferin, free iron, phenotypes of lymphocytes.
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Authors
Dobrodeeva Liliya K. dobrodeevalk@mail.ru
Institute of Environmental Physiology, Ural Branch of Russian Academy of Sciences, doctor of medical sciences, professor, deputy director for research.
Russian Federation 163000, Arkhangelsk, prospekt Lomonosova, 249
Zubatkina Irina S. izubatkina@gmail.com
Diagnostic Center of International Institute of Biological Systems named after S.M. Berezin (Saint-Petersburg), candidate of biological sciences, medical physicist. Russian Federation 191036, Saint-Petersburg, str. 6-th Sovetskaya, 24.
Samodova Anna V. annapoletaeva2008@yandex.ru
Federal State Scientific Institution Institute of Environmental Physiology, Ural Branch Russian Academy of Science; Candidate of Biology, senior research associate of laboratory of regulatory mechanisms of immunity
Russian Federation 163000 g. Arhangel’sk. pr. Lomonosova, 249
Zubatkina Olga V. ozbiochem@gmail.com
Northern State Medical University (Arkhangelsk), doctor of biological sciences, professor, head of department of biomedical chemistry
Russian Federation 63000, Arkhangelsk, Troitskii prospekt, 51.
Malahova Margarita J. prof-malachova@mail.ru
Northwestern State Medical University. II Mechnikov, doctor of medical sciences, professor of clinical laboratory diagnostics
Russian Federation, St. Petersburg, ul. Kirochnaya d.41
Popov Andrei A. biochem66@gmail.com
Northern State Medical University (Arkhangelsk), candidate of biological sciences, dozent, associate professor of department of biomedical chemistry
Russian Federation 63000, Arkhangelsk, Troitskii prospekt, 51