Research of antibacterial properties of synthetic peptides of the active center GM-CSF, various defensins and the substances received from supernatants CD34+45 — cages of predecessors hemopoesis.

Zurochka A.V., Zurochka V.A., Kostolomova E.G.,
Dobrynina M.A., Suchovey Y.G., Gricenko V.A.

Summary.

Studied antibacterial action of synthetic peptides of the
GM-CSF active center and the substances received from supernatantes
CD34+45 — cells predecessors of hemopoesis. It has been revealed that
GM-CSF peptides and supernatantes cages possess the expressed antibacterial
activity, thus the combination of the given substances possesses
more expressed activity in comparison with separate substances.
Possible mechanisms of the revealed effects of synthetic peptides and
substances from supernatantes are discussed CD34+45-.

Key words:

GM-CSF peptides, CD34+45 — cells, antibacterial activity

Authors
Zurochka Alexander V.
Establishment of the Russian Academy of
Sciences Institute of Immunology and Physiology, Ural, RAS

Zurochka Vladimir A.
Establishment of the Russian Academy of
Sciences Institute of Immunology and Physiology, Ural, RAS

Dobrynin Maria A.
Establishment of the Russian Academy of
Sciences Institute of Immunology and Physiology, Ural, RAS

Suhovey Yury G.
Tyumen Branch of Institute of Medical Sciences
institutions of Clinical Immunology

Kostolomova Elena G.,
Tyumen Branchof Institute of Medical Sciences
institutions of Clinical Immunology.

Gritsenko Victor A.,
The establishment of the
Russian Academy of Sciences Institute of Cellular and Intracellular Symbiosis, Ural
Branch of RAS.
e-mail: v_zurochka@mail.ru;

Russia, 454005 Chelyabinsk, street Television the house 6, apartment 36