Interaction of Hydrocortisone and Adrenaline Hydrochloride in Regulation of Lymphocyte Proliferation In Vitro

Shilov Ju.I., Shilov S.Ju., Valieva Ju.V.

Institute of Ecology and Genetics of Microorganisms of Ural Branch of the Russian Academy of Sciences; Perm State National Research University, Perm, Russian Federation

Abstract. The sexual dimorphism of changes of neutrophil phagocytic activity of aging rats was found. Injections of dehydroepiandrosterone into old rats modifies these changes in relation with the sex of animals.

Keywords: aging, neutrophils, phagocytosis, dehydroepiandrosterone

REFERENCES
1. Labrie F., Luu-The V., Belanger A., Lin S-X., Simard J., Pelletier G., Labrie C. Is dehydroepiandrosterone a hormone? J. Endocrinol. – 2005. – Vol. 187 (2). – P. 169–196.
2. Koziol-White C.J., Goncharova E.A., Cao G., Johnson M., Krymskaya V.P., Panettieri R.A. Jr. DHEA-S inhibits human neutrophil and human airway smooth muscle migration. Biochim. Biophys. Acta. – 2012. – Vol. 1822(10). – P. 1638-1642.

Authors
Shilov Jurii I., e-mail jshilov@mail.ru
Institute of Ecology and Genetics of Microorganisms of the Ural Branch of the Russian Academy of Sciences (IEGM UB RAS)
MD, PhD, associated professor, leading researcher of Laboratory of Ecological Immunology
Goleva Street 13, Perm 614081, Russian Federation
Perm State National Research University
associate professor of Department of Microbiology and Immunology
Bukireva street, 15, Perm, 614990, Russian Federation
Academician E.A. Wagner Perm State Medical Academy of Ministry of Healthcare of the Russian Federation (Acad. E.A. Wagner PSMA)
associate professor of Department of Immunology
Petropavlovskaja street, 26, Perm, 614000, Russian Federation

Shilov Stanislav Ju., stshilov@mail.ru.
IEGM UB RAS, MD, PhD, junior researcher of Laboratory of Ecological Immunology

Valieva Julija V.
Perm State National Research University, graduate student, master programme on Department of Microbiology and Immunology at Biological Faculty