THE CLINICAL AND PATHOGENEGICAL FEATURES OF PERIPHERAL NERVOUS SYSTEM OF PATIENTS WITH ESKD

 Tereshchuk M.A, Volkova L.I., Zlokasov V.B.

Clinical experience

Abstract.

Complications of the nervous system can be considered like obligate condition of patients with end-stage kidney disease (ESKD). Pathological mechanisms which cause disorders of nervous system of patients with ESKD, are the complex processes connecting with progressive kidney dysfunction: excretory and endocrine. Lesion of peripheral nervous system dependent from metabolic changes is wide presented, but is rare detected, approximately in 60% cases. Uremic polyneuropathy characterized buy symmetrical distal defeat limbs likes senso-motor polyneuropathy. Frequent violations of uremic polyneuropathy are restlessleg syndrome, “burning in the feet” syndrome, syndrome of paradoxical thermal sensitivity. Early detection and adequate interpretation the symptoms of lesion in nervous system are necessary for prognoses estimate of appeared neurological deficits in patients with chronic kidney disease on extra renal purification of blood stage.

Key words:

end-stage kidney disease, complications in nervous system, uremic polyneuropathy, restlessleg syndrome, “burning in the feet” syndrome, syndrome of paradoxical thermal sensitivity, vegetative dysfunction.

Autors:

Tereshchuk Marina A.

Sverdlovsk Clinical Hospital 1

185, Volgogradskaya, Ekaterinburg, Sverdlovsk Clinical Hospital 1, Russia, 620102

e-mail: terma@okb1.ru

Volkova Larisa I.

Doctor of medicine, Chief of department Neurology and neurosurgery UGMA

3, Repina, Ekaterinburg, Ural State Medical Academy, Russia, 620219

e-mail: vli@okb1.ru

Zlokasov Vladimir B.

Sverdlovsk Clinical Hospital 1,Chief of Dialysis department

185, Volgogradskaya, Ekaterinburg, Sverdlovsk Clinical Hospital 1, Russia, 620102

e-mail: terma@okb1.ru