Clinical and laboratory features in accordance with various options of morphological changes of multislice computed tomography in patients with chronic obstructive pulmonary disease
Selezneva E.L., Zhdanova T.V., Maslova L.A.
Abstract. COPD (chronic obstructive pulmonary disease) is a heterogeneous disease associated with significant morbidity and mortality. Current diagnostic criteria based on the presence of fixed airflow obstruction and symptoms do not integrate the complex pathological-morphological changes occurring within lung. This article is about the issue of differentiation of groups of patients with chronic obstructive pulmonary disease. The analysis of clinical and laboratory symptoms of patients with chronic obstructive pulmonary disease II-IV stage depending on the morphological changes of multislice computed tomography. The study identified the following groups of patients: unchanged CT lung with pneumosclerosis from bullous emphysema, and bronchiectasis with related clinical and laboratory signs.
Keywords: chronic obstructive pulmonary disease, multislice computed tomography imaging (CT imaging), clinical and laboratory signs
REFERENCES
1. Global Strategy for the Diagnosis, Management and Prevention of COPD, Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2014; URL: http://www.goldcopd.org.
2. Han М.К. Chronic obstructive pulmonary disease phenotypes: the future of COPD / Han М.К., A. Agusti, P.M. Calverley. American Journal of Respiratory and Critical Care Medicine. – 2010. — 182(5). – Р. 598-604.
3. Friedlander A.L. Phenotypes of chronic obstructive pulmonary disease. A.L. Friedlander, D. Lynch, L.A. Dyar, R.P. Bowler. COPD. — 2007. – 4. – Р. 355-384.
4. Gorbunov N.A. Osobennosti luchevoj diagnostiki hronicheskoj obstruktivnoj bolezni legkih na sovremennom jetape. N.A. Gorbunov, V.Ja. Laptev, V.I. Kochura. Luchevajadiagnostika i terapija. – 2011. — 4(2). – S. 33-39.
5. Zavadovskaja V.D. KTVR v rannej diagnostike HOBL. V.D. Zavadovskaja, O.V. Rodionova. Dostizhenija sovremennoj luchevoj diagnostiki v klinicheskoj praktike: tezisy materialov IV-j regional'noj konferencii. Tomsk. – 2006. – S. 161-165.
6. Budnevskij A.V. Rol' komp'juternogo registra v ocenke jeffektivnosti upravlenija lechebno-diagnosticheskim processom u bol'nyh hronicheskoj obstruktivnoj bolezn'ju legkih. A.V. Budnevskij. Sistemnyj analiz i upravlenie v biomedicinskih sistemah. – 2013. — 12(3). – S. 618-621.
7. Budnevskij A.V. Osobennosti terapii i reabilitacii bol'nyh hronicheskoj obstruktivnoj bolezn'ju legkih s soputstvujushh ej patologiej. A.V. Budnevskij. Nauchno-medicinskij vestnik Central'nogo Chernozem'ja. – 2011. – 43. – S. 8-15.
8. Nacional'nye rekomendacii po profilaktike, diagnostike I lecheniju arterial'noj gipertonii. (Rekomendacii razrabotany jekspertami Vserossijskogo nauchnogo obshhestva kardiologov v 2001 godu I utverzhdeny na Rossijskom nacional'nom kongresse kardiologov 11 oktjabrja 2001 g., vtoroj peresmotr Rekomendacij osushhestvlen v 2004 g.)
9. West J.B. Pulmonary Pathophysiology. J. BWest. The Essentials, 7thed. Baltimore: Lippincott Williams & Wilkins. – 2007. – Р. 1–224.
10. Makita H. Characterisation of phenotypes based on severity of emphysema in chronic obstructive pulmonary disease. H. Makita, Y. Nasuhara, K. Nagai. Thorax. – 2007. – 62. – Р. 932–937.
11. Aver'janovaA.V. Jemfizemalegkih: Monografija. A.V. Aver'janova (Serija monografij Rossijskogo respiratornogo obshhestva; gl. red. Serii A.G. Chuchalin). – M.: Izdatel'skij dom «Atmosfera». – 2009. – S. 136.
Authors
Selezneva Elena L.
postgraduate of Department of Internal Medicine Propaedeutics of Ural State Medical University of Department of Health of the Russian Federation, Yekaterinburg, Russian Federation
Zhdanova Tat'jana V.
Doctor of Medical Sciences, professor, head of Department of Internal Medicine Propaedeutics of Ural State Medical University of Department of Health of the Russian Federation, Yekaterinburg, Russian Federation
Maslova Larisa A.
Candidate of Medical Sciences, assistant professor of Department of Internal Medicine Propaedeutics of Ural State Medical University of Department of Health of the Russian Federation, Yekaterinburg, Russian Federation
State Educational Institution of Higher Professional Education Ural State Medical University of Department of Health of the Russian Federation, Yekaterinburg, Russian Federation Yekaterinburg, Repin Street, 3, 620109
selezneva.elena.1989@mail.ru
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)

