Correction of Dysbiosis Treatment-and-Prophylactic Means Suzinon in the Treatment of Patients with Gynecologic Profile
Poroshina D.V., Trofimova N.M., Rasskazenkova E.A., Zabokritskiy N.A., Krivopalov S.A.
Scientific research Institute of maternity and infancy; Ural State Medical University, department of obstetrics and gynecology; Ural State Medical University, department of pharmacology and clinical pharmacology; Institute of Immunology and Physiology of the Ural Branch of the Russian Academy of Sciences, Yekaterinburg, Russian Federation
Abstract. In the article the actual questions dedicated to the correction of dysbiosis, developed by the authors metabolic probiotic treatment-and-prophylactic suzinon. The obtained results show that for the normalization of dysbacteriosis vaginal biotope of gynecological patients with bacterial vaginosis, vaginal candidiasis and nonspecific vaginitis, in order to restore and maintain the normal vaginal microflora most adequate metabolic sredstvom is bicomponent metabolic drug suzinon based highly active probiotic strains of bacilli and lactobacilli. After 2–3 weeks after the drug is stable recovery of the normal vaginal flora, elimination of facultative and obligatory anaerobic microflora, increasing the number of lactobacilli, the disappearance of inflammation.
Keywords: vaginal microflora, dysbiosis, correction, suzinon, metabolic drug, bacterial vaginosis
REFERENCES
1. Zabokritskiy N.A., Larionov L.P., Bakhurinskih A.B. Biomedicine, 2010. Vol. 1, no. 5. P. 85-86.
2. Zabokritskiy A.N., Morozov M.P., Zabokritskiy N.A. et al. Patent RF, 2008, no. 2367454.
3. Zabokritskiy A.N., Larionov L.P., Plokhushko E.N., Vasilyev P.G. et al. Chemical-pharmaceutical journal, 2006. Vol. 40, no. 5. P. 3-7.
4. Orishak E.A., Scheglov V.S., Nilova L.U. Problems of medical Mycology, 2013. Vol. 15, no. 4. P. 74-80.
5. Pozdnyakova I.G., Nazarova L.S. Vestnik Saratovskogo gosagrouniversiteta them. N.I. Vavilov, 2011, no. 09. P. 6-9.
6. Larionov L.P., Zabokritskiy N.A., Bakhurinskih M.A., Bakhurinskih A.A. Biomedicine, 2010. Vol. 1, no. 5. P. 102-104.
Authors
Poroshina Daria Vladimirovna
Scientific research Institute of maternity and infancy
Obstetrician-gynecologist
Repina street, 1, Ekaterinburg, Russian Federation, 620028
Trofimova Nadezhda Michailovna
Scientific research Institute of maternity and infancy
Obstetrician-gynecologist
Rasskazenkova Ekaterina Andreevna
The Ural state medical University, Department of obstetrics and gynecology
Obstetrician-gynecologist
Repina street, 1, Ekaterinburg, Russian Federation, 620028
Zabokritskiy Nikolay Alexandrovich.
The Ural state medical University, department of pharmacology and clinical pharmacology
Candidate of medical Sciences, associate Professor of pharmacology and clinical pharmacology
Repina street, 3, Ekaterinburg, Russian Federation, 620028
Institute of immunology and physiology, Ural branch of Russian Academy of Sciences
senior researcher of the laboratory of immunophysiology and immunopharmacology.
Pervomayskay street, 106, Ekaterinburg, Russian Federation, 620219
Krivopalov Sergey Alexandrovich
Institute of immunology and physiology, Ural branch of Russian Academy of Sciences
Postgraduate student, junior researcher, laboratory of immunophysiology and immunopharmacology