Key Peculiarities of Protein-energy Metabolism and Nutrtional Status Impairment of Cerebral ICU Patients during Early Rehabilitation Period in Specialized Medical Center
DOI: 10.22138/2500-0918-2018-15-1-12-19
I.N. Leiderman, А.А. Belkin, R.T. Rakhimov, N.S. Lipovka, V.A. Belkin
Clinical Institute of Brain, Yekaterinburg, Russian Federation;
Ural State Medical University Yekaterinburg, Russian Federation
Abstract The development of early and ICU rehabilitation technologies opens new prospects for improving the quality of life and restoring the physical functions and social adaptation of patients in intensive care units with acute cerebral insufficiency. However, very often the effective rehabilitation is hampered by severe disorders of nutritional status and protein-energy metabolism that occurred during intensive care of critical illness.
Aim of the study: To assess the main parameters of the nutritional status and protein-energy metabolism of ICU patients with acute cerebral insufficiency, entering the stages of medical rehabilitation. Materials and methods: Prospective cohort trial of most important parameters of protein-energy metabolism and nutritional status was provided in 107 Institute of Brain ICU department patients with cerebral critical illness. Results: The main metabolic features that could be identified as a result of our study were reduced markers of both the visceral and somatic protein pool, hypoalbuminemia, hypotransferrinemia, as well as severe body mass deficit and a decrease in a number of anthropometric parameters. On the contrary, such indicators as body mass index (BMI), urinary nitrogen excretion and absolute lymphocyte count in peripheral blood were within the normal range even in patients with body weight loss more than 20%.
Keywords: acute cerebral insufficiency, rehabilitation, protein-energy metabolism, nutritional status
Received 13.11.2017
Forcitation:
I.N. Leiderman, А.А. Belkin, R.T. Rakhimov, N.S. Lipovka, V.A. Belkin. Key Peculiarities of Protein-energy Metabolism and Nutrtional Status Impairment of Cerebral ICU Patients during Early Rehabilitation Period in Specialized Medical Center. Vestn. Ural. Med. Akad. Nauki. = Journal of Ural Medical Academic Science. 2018, Vol. 15, no. 1, pp. 12–19. DOI: 10.22138/2500-0918-2018-15-1-12-19 (In Russ)
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Authors
Ilya N. Leiderman
Ural State Medical University
Dr. Sci. (Med.), Professor of Anesthesiology and Critical Care Medicine Chair
Clinical Institute of Brain
ICU Department Chief
inl230970@gmail.com
Andrey A. Belkin
Ural State Medical University
Dr. Sci. (Med.), Professor of Anesthesiology and Critical Care Medicine Chair
Clinical Institute of Brain
Director
belkin@neuro-ural.ru
Rinat T. Rakhimov
Clinical Institute of Brain
MD,ICU Department
kim@neuro-ural.ru
Nadegda S. Lipovka
Clinical Institute of Brain
MD, Chief of Neurological Department
kim@neuro-ural.ru
Vladimir A. Belkin
Clinical Institute of Brain
MD, Neurological Department
kim@neuro-ural.ru
Clinical Institute of Brain
Russian Federation, Sverdlovsk region, Berezovski, Shilovskaya Street 28, building 6
kim@neuro-ural.ru
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