FEATURES OF BREAST CANCER TISSUE VASCULARIZATION

Brilliant A. A., Sazonov S. V., Zasadkevich Y. M.

GAHO SR Institute of Medical Cell Technologies;
GBEO HPE Ural State Medical University,
Yekaterinburg, Russian Federation

Abstract.
The vascular network by identification of capillary endothelium was studied. In breast cancer tissue the number of ripening capillaries in 5 times higher than in intact tissue, at the same time their proportion does not change during the increase of cancer proliferation. The proportion of mature capillaries decreases with the increase of proliferative activity of the tumor.

Key words:
breast cancer, vascularization, CD31, CD34, VEGF, VEGFR

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Authors
Brilliant Aleksandr A. 
Institute of Medical Cell Technologies
PhD, senior reseacher
alex_brilliant@mail.ru

Sazonov Sergey V.
Institute of Medical Cell Technologies
Ural State Medical University
PhD, MD, Professor, the Head of the department of histology, cytology and embryology of Ural State Medical University and the laboratory of pathomorphology of Institute of Medical Cell Technologies
prof-ssazonov@yandex.ru

Zasadkevich Yulia M. 
Institute of Medical Cell Technologies
Ural State Medical University

PhD student, researcher
yulkat@bk.ru

Government Autonomic Healthcare Organization of Sverdlovsk Region «Institute of Medical Cell Technologies»
Russian Federation, 620000, Vilonova St., 76 a, Yekaterinburg

Government Budget Educational Organization «Ural State Medical University» of Ministry of Healthcare of Russian Federation, Department of histology, cytology and embryology
Russian Federation, 620028 Repina St., 3, Yekaterinburg