Polisystem disturbances in the body of patients with brain tumors

Muhacheva M. V., Bein B. N., Chuprakov P. G.

Kirov State Medical Academy the Ministry of Health, Kirov, Russian Federation

Abstrakt.
Brain tumors, in addition to local and general cerebral manifestations accompanied hypercoagulable disorders and neuroendocrine secretion. Described as paraneoplastic reaction. At 99 neurooncological patients, compared with 50 healthy individuals, complex studied clinical and neurological data, indicators of immune protection in various parts of immunity, the state of the central autonomik regulation (heart rate variability caused by autonomic potentials) and the content of free amino acid spectrum of blood serum. The analysis of cumulative changes to the average values of the dependent variable and the correlation with the distribution of the parameters of all the factors in a multidimensional space for comparable groups of observations. The change homeostasis in tumor patients, as well as adaptive responses, allowing considered «focal brain damage» as «tumor disease» of the whole body of patients. This requires a holistic approach to the treatment of neuro-oncological patients.

Key words:
brain tumors, immunity, central autonomik regulation of heart rate, blood amino acid spectrum, multiple effects on the body

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Authors
Mukhacheva Marianna V.
PhD, associate professor, Department of neurology, neurosurgery

Beyn Boris N. 
Head of the Department of Neurology, Neurosurgery, Doctor of Medical Science, professor.

Chuprakov Pavel G. 
Associate Professor, Department of Applied Mathematics and Computer Science Vyatka State University, PhD.

Kirov State Medical Academy the Ministry of Health, Kirov
Russian Federation, Kirov Vorovskogo Street. d. 42, Building 4
marvit75@yandex.ru