Problem issues of mineral metabolism among residents of the Arctic Territories

DOI: 10.22138/2500-0918-2019-16-2-96-102

УДК 577.118 (571)

A.L. Gorbachev

North-Eastern State University, Magadan, Russian Federation

Abstract. Objective: to give a biogeochemical characterization of the northern regions and to justify the need for medical and environmental studies of the bioelemental status of Arctic populations of migrants and aboriginal people. Methods: review of the literature on biogeochemical studies of the northern territories for the period 1980-2018. Results. Given the climatic characteristics of areas of the North, including the geochemical environment. It is shown that the elemental status of the inhabitants of the North was be analyzed mainly in the inhabitants of the circumpolar regions. Due to objective difficulties, the Arctic regions remain practically unexplored. Emphasis is placed on man-made pollution of the biosphere of the northern regions with heavy metals, and above all with mercury, which has a neurotoxic effect. By the example of mercury and selenium, antagonistic relations between the chemical elements in a living organism are shown, resulting in the formation of secondary microelementoses. It was suggested that in order to develop the Arctic territories of Russia, it is necessary to conduct geochemical zoning of the modern Arctic regions, and the identification of the “predisposition” of certain territories to biogeochemical endemys.

Keywords: North, microelements, disadaptation, endemia

Received 19.04.2019.

For citation:
Gorbachev A.L. Problem issues of mineral metabolism among residents of the Arctic territories. Vestn. Ural. Med. Akad. Nauki. = Journal of Ural Medical Academic Science. 2019, Vol. 16, no. 2, pp. 96-102. DOI: 10.22138/2500-0918-2019-16-2-96-102 (In Russ)

REFERENCES
1. Skalny A.V. The development of the concept of bioelements and the prospects of bioelementology. Mikroehlementy v medicine. 2009. Vol.10. No. 3-4. pp.1-6. (In Russ).
2. Agadzhanyan N.A., Skalny A.V., Detkov V.Yu. Elemental portrait of a person: morbidity, demography and the problem of nation health management. EHkologiya cheloveka. 2013. No.11. pp.3-12. (In Russ).
3. Skalny A.V. Assessment and correction of the elemental status of the population — a promising direction of domestic health care and environmental monitoring. Mikroehlementy v medicine.2018. Vol.19.No.2.pp. 5-13. (In Russ).
4. Gorbachev A.L., Efimova A.V., Lugovaya Ye. A., Bulban A.P. Features of the elemental status of residents of various natural-geographical areas of the Magadan region. EHkologiya cheloveka. 2003. No.6. pp.12-16. (In Russ).
5. Gorbachev A.L., Dobrodeeva L.K., Tedder Yu.R., Shatsova E.N. Biogeochemical characteristics of the northern regions. The trace element status of the population of the Arkhangelsk region and the forecast development of endemic diseases. EHkologiya cheloveka. 2007. No.1. pp.4-11. (In Russ).
6. Gorbachev A.L. Skalny A.V., Lugovaya Ye. A. Some regularities of the elemental status of residents of the northern regions of Russia against the background of the biogeochemical characteristics of the North. Vestnik vosstanovitel'noj mediciny. 2008. No.5A (28). pp.22-25. (In Russ).
7. Korchina T.Ya., Sorokun I.V. Some physiological indicators and elementary status of the indigenous population of the Khanty-Mansiysk Autonomous Okrug. Uspekhi sovremennogo estestvoznaniya. 2006. No1. pp. 89-90. (In Russ).
8. Skalny A.V. Ecological and physiological rationale for the effectiveness of the use of macro — and micronutrients for homeostasis disorders in patients from different climatic and geographical regions: Diss. … dokt. med. nauk. M. 2000. 352 p. (In Russ).
9. Egorova G.A. Elemental status of the adult population living in different medical-geographical zones of the Republic of Sakha (Yakutia). EHkologiya cheloveka. 2007. No,1. pp.55-59. (In Russ).
10. Petrova P.G., Egorova G.A. Ecology and human health in the North. Sibirskij medicinskij zhurnal. 2007. No.2a. pp.54-58. (In Russ).
11. Alekseeva I.A., Khotimchenko S.A., Stepchuk M.A., Sukhanov B.P. To the question of the state of mineral metabolism in the indigenous and alien population living in the regions of the Far North. Medicina truda i promyshlennaya ehkologiya.1996. No.6. pp.43-46. (In Russ).
12. Zorina D.Yu., Batsevich V.A. The trace element status of the indigenous population of the Arctic (Chukchi, Eskimos) according to the results of hair analysis. Vestnik Moskovskogo universiteta. Seriya XXIII. Antropologiya.2011. No.4. pp.105-111. (In Russ).
13. Dudarev A.A. Persistent polychlorinated hydrocarbons and heavy metals in the Arctic biosphere. The main patterns of exposure and reproductive health of indigenous people. Biosfera. 2009. No. 2. pp.186-202. (In Russ).
14. Comparative characteristics of lead intoxication and cadmium intoxication of the population of the Khanty-Mansiysk Autonomous Okrug. Gigiena i sanitariya. 2011.No.3. pp.8-10. (In Russ).
15. Gorbachev A.L. Mercury as a priority environmental pollutant. Mikroehlementy v medicine. 2016. Vol..17. No. 2. pp.3-9. (In Russ).
16. Kern J.K., Geier D.A., Sykes L.K., Haley B.E., Geier M.R. The relationship between mercury and autism: A comprehensive review and discussion. J. Trace Elem.Med.Biol. 2016. Vol. 37. pp. 8–24.
17. Marachev A.G., Zhavoronkov A.A. Acclimatization iron deficiency. Fiziologiya cheloveka. 1987. Vol.13. No 4. pp.640 –646. (In Russ).
18. Kucher A.N. Gene-environment interactions as the basis for the formation of health. EHkologicheskaya genetika. 2017. Vol.15. No.4. pp.19-32. (In Russ).
19. Prokhorov B. B. Population ecology in the Russian North. Problemy prognozirovaniya. 1999. No. 3. pp. 130-142. (In Russ).
20. Kaznacheev V.P. Modern aspects of adaptation. Novosibirsk: Nauka, 1980. 190 p. (In Russ).
21. Hasnulin V.I. Introduction to polar medicine. Novosibirsk: SO RAMN, 1998. 337 p. (In Russ).
22. Gudkov AB, Labutin N.Yu. The influence of specific factors of the Arctic on the functional state of the human body well. EHkologiya cheloveka. 2000. No.2. pp.18-20. (In Russ).
23. Kaznacheev V.P., Panin L.E., Kovalenko L.A. Actual problems of rational nutrition of the alien population of the Polar region and the natives of the North. Voprosy pitaniya. 1980. No. 1. pp. 23-27. (In Russ).
24. Panin L.E. Rational nutrition in the North — the basis of primary prevention. Problemy sovremennogo social'nogo razvitiya narodnostej Severa. Pod red. V.I. Bojko, YU.P.Nikitina, A.I. Solomahi. Novosibirsk: Nauka. Sib.otd.1987. pp.223-230. (In Russ).
25. Gyrgolkau L. A., Shcherbakova L. V., Ivanova M. V. Blood lipids and the frequency of dyslipoproteinemia in the indigenous people of Chukotka. Byulleten' Sibirskogo otd. RAMN. 2011. Vol. 31. No. 5. pp.79-83. (In Russ).
26. Sevostyanova E.V. Features of the lipid and carbohydrate metabolism of man in the North (literature review). Byulleten' sibirskoj mediciny, 2003. Vol.12. No.1. pp.93-100. (In Russ).
27. Malyarchuk B.A. Genetic structure, adaptation and health of the indigenous population of Northeast Asia (current state of the problem). Vestnik Severo-Vostochnogo nauchnogo centra DVO RAN, 2017. No.2. pp. 118-127. (In Russ).
28. Krivoshchekov S.G., Okhotnikov S.V. Production migrations and human health in the North. Novosibirsk: SO RAMN, 2000. 117 p. (In Russ).
29. Efremov V.V. To the history of studying nutrition in the Soviet North. Voprosy pitaniya. 1985.No.5. p.71-75. (In Russ).
30. Chanchayeva E.A. On the question of the adequacy of nutrition of the aboriginal population of Siberia. Literature review. EHkologiya cheloveka. 2010. No.3. pp.31-34. (In Russ).
31. Borinskaya S.A., Kozlov A.I., Yankovsky N.K. Genes and food traditions. EHtnograf. obozrenie. 2009. No.33. pp.117-137. (In Russ).
32. Kozlov AI, Nuvano V., Zdor E. Diet of Chukotka. Himiya i zhizn'. 2008. No. 4. pp. 42-45. (In Russ).
33. Kershengolts B.M. Non-specific biochemical mechanisms of adaptation of organisms to extreme environmental conditions. Nauka i obrazovanie. 1996. No.3. pp.130-138. (In Russ).
34. Bogoslovskaya L. Slugin I., Zagrebin I., Krupnik I. Basics of marine hunting: Nauchno-metodicheskoe posobie. M.-Anadyr': Institut Naslediya, 2007. 480 p. (In Russ).
35. Greenberg C.R., Dilling L.A., Thompson G.R. et al. The paradox of the carnitine palmitoyl transferase type 1a P479L variant in Canadian Aboriginal populations. Mol.Genet. Metab. 2009. Vol.96. pp. 201-207.
36. Recommendations for monitoring salt iodization programs and assessing the status of iodine provision of the population. Klinicheskaya i ehksperimental'naya tireoidologiya. 2018. Vol.. 14. No.2. pp. 100–112. doi: 10.14341/ket9734 (In Russ).
37. Materials of the state report «On the state of sanitary and epidemiological well-being of the population in the Chukotka Autonomous Region in 2016: g. Anadyr', 2017. 127 p. (In Russ).

Author
Anatolij L. Gorbachev
North – Eastern State University
Dr. Sci. (Biological), Professor, Leading Researcher
Portovaya str. 13 Magadan 685000 Russian Federation
gor000@mail.ru

 

Лицензия Creative Commons

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)

 
 
 

Authorization