The Syndrome of Endogenous Intoxication in the Flow of Acute and Chronic Hepatitis B with Extrahepatic Manifestations

Kuznetsov P.L., Borzunov V.M., Bessonova E.N., Ruzanov E.V., Ruslyakov D.V.

Abstract.

HBV-infection is considered as a systemic generalized
infection, which may cause extrahepatic manifestations of the
disease. Syndrome of endogenous intoxication, as a component of
intoxication syndrome, in varying degrees is present in patients
with acute and chronic viral hepatitis B with extrahepatic lesions.
The dynamics of the markers of endogenous intoxication syndrome
examined in 211 patients with HBV-infection with periarteritis
nodosa and isolated lesions of the joints, skin, cardiovascular
system and kidneys. Results reflect a large amount of endogenous
intoxication in patients with periarteritis nodosa and renal disease.

Keywords: viral hepatitis В, a syndrome of endogenous intoxication

Authors
Kuznetsov Pavel L.
SBEI HPE Ural State Medical Academy, Ministry of health and social development
of Russia
Borzunov Viktor M.
SBEI HPE Ural State Medical Academy, Ministry of health and social development
of Russia
Bessonova Elena N.
SHCI Sverdlovsk regional hospital №1, Russian Federation, Ekaterinburg
Ruzanov Evgeni V.
SBEI HPE Ural State Medical Academy, Ministry of health and social development
of Russia
Ruslyakov Dmitri V.
SBEI HPE Ural State Medical Academy, Ministry of health and social development
of Russia
620102, Russia, Ekaterinburg, Volgogradskaya st., 189.
e-mail:kupal@mail.ru