Modern Approaches to Predicting Primary Weakness of Labour at Primiparous Women
DOI: 10.22138/2500-0918-2017-14-2-147-155
N. M. Milyaeva
Ural State Medical University, Yekaterinburg, Russian Federation
Abstract. Among all anomalies of labor, the bottom of the first places is the primary weakness of labor, in 70–80 % of cases develop in young primiparas of somatically healthy women. At the same time, maternal and perinatal morbidity, death of fetuses and newborns, the growth of operative abdominal and vaginal births and birth trauma continue to be high. The purpose of the study: optimization of prenatal prognosis of primary weakness of labor activity to improve the outcome of labor. Materials and methods: A real prospective, continuous, comparative cohort randomized trial to identify risk factors and prognosis of obstetrical pathology is performed during gestation at 39.9–40.6 weeks gestation in 287 primiparous women. On the fact of clinical course of childbirth, two groups were formed: I primary group (n = 119) — timely delivery with primary SRS; II comparison group (n = 168) — timely labor with coordinated labor activity (KRD). All women in the prenatal period under the term of full-term pregnancy underwent clinical and laboratory-instrumental research in accordance with the available standards of management of pregnant women, as well as the study of enzymes of cellular energy exchange and molecular-genetic study of polymorphism of energy metabolism genes. The results of the work: a model for predicting the primary weakness of labor was proposed based on a complex of clinical, biophysical, biochemical, molecular genetic, functional research methods to improve the outcome of timely delivery in young primiparous women.
Keywords: weakness of labor activity, prognosis, obstetrics
Received 30.05.2017
For citation:
Milyaeva N.M. Modern approaches to predicting primary weakness of labour at primiparous women. Vestn. Ural. Med. Akad. Nauki = Jour. Ural Med. Acad. Science. 2017, no. 2, pp. 147–155. DOI: 10.22138/2500-0918-2017-14-2-147-155 (In Russ.)
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Author
Natalia M. Milyaeva
Ural State Medical University
Сand. Sci. (Med.), Assistant Professor of Obstetrics and Gynecology
Str. Repin, 3, Yekaterinburg, 620028, Russian Federation
soneta64@rambler.ru
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