COMPARATIVE ANALYSIS OF PARAMETERS OF LIPID AND CARBOHYDRATE MATABOLISM IN ABORIGINAL AND NON-ABORIGINAL YOUNG PEOPLE IN THE ARCTIC REGION
DOI: 10.22138/2500-0918-2018-15-2-229-238
T.V. Tretyakova, O.S. Vlasova, N.F. Baranova
Institute of Environmental Physiology of N. Laverov Federal Center for Integrated Arctic Research of the RAS (FCIARctic), Arkchangelsk, Russian Federation
Abstract. The purpose of the investigation is to study the characteristics of the lipid and carbohydrate metabolism parameters in the young people of the Arctic region, depending on ethnic affiliation. Materials and methods. The investigation involved girls and boys aged 16–18 years living in the Chukotka Autonomous Okrug and related to the aboriginal (Chukchi, Chuvans, Eskimos, Evens, etc.) and non-aboriginal (Caucasoid) populations. There were determined serum levels of lipid and carbohydrate metabolism parameters by spectrophotometry method and the content of fatty acids by the gas-liquid chromatography method. statistical processing of data is performed by nonparametric methods. Results. Among the girls, there were significant changes in the level of triglycerides and very low-density lipoprotein (VLDL), which were higher among non-aboriginal representatives. In the group of aboriginal people, especially among the male contingent, the content of fatty acids (FA) was higher, without significant fluctuations of the other lipid metabolism parameters. In considering the parameters of carbohydrate metabolism in aboriginal girls in relation to non-aboriginal ones, there was established a decrease in the glucose and pyruvate levels. Both the aboriginal and non- aboriginal populations had increased rates of esterification, atherogenicity, LAC/PIR ratio due to low pyruvate and high lactate levels, with low glucose content in the background there was low values of the polyunsaturated FA: dihomo-?-linolenic, arachidonic, eicosapentaenoic and docosahexaenoic, as well as the saturated FA: palmitic and stearic. The conclusion. The lowering of the triglyceride, VLDL, glucose levels and an increase of FA concentrations in Aboriginal groups are a reflection of ethnic differences in metabolic processes of the youth population in the context of chronic adaptationto the conditions of the North. Regardless of the ethnic affiliation, there have been revealed an increase in the activity of cholesterol esterification and a decrease in anti-atherogenic defense with a lack of essential polyunsaturated and long chain saturated FAs, as well as a low glucose level and the predominance of anaerobic oxidation processes in the background.
Keywords: lipid metabolism, carbohydrate metabolism, fatty acids, Arctic, North, aboriginal and non-aboriginal population, boys and girls
Received 09.04.2018
For citation:
Tretyakova T.V., Vlasova O.S., Baranova N.F. Comparative analysis of parameters of lipid and carbohydrate matabolism in aboriginal and non-aboriginal young people in the Arctic region. Vestn. Ural. Med. Akad. Nauki. = Journal of Ural Medical Academic Science. 2018, Vol. 15, no. 2, pp. 229–238. DOI: 10.22138/2500-0918-2018-15-2-229-238 (In Russ)
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Authors
Tatyana V. Tretykova
Cand. Sci. (Biol.), Senior researcher of the Laboratory of Biological and Inorganic Chemistry
tretyakova.t73@mail.ru.
Olga S. Vlasova
Cand. Sci. (Biol.), Senior researcher of the Laboratory of Biological and Inorganic Chemistry
olgawlassova@mail.ru.
Nina F. Baranova
Junior researcher of the Laboratory of Biological and Inorganic Chemistry
baranova.nfb@yandex.ru.
Institute of Environmental Physiology of N. Laverov Federal Center for Integrated Arctic Research of the RAS
Russian Federation, 163061, Arkhangelsk, Lomonosov Ave., 249
