STRUCTURE OF ALLERGOSENSITIZATION IN CHILDREN WITH ALLERGOPATOLOGIES IN THE KALININGRAD REGION
A.Z. Markhaychuk¹, M.A. Vulf², O.G. Khaziakhmatova², L.S. Litvinova²,
A.G. Goncharov², A. Yu. Gorbunova³, A. M. Malyarov¹
DOI: 10.22138/2500-0918-2022-19-3-339-346
¹ State Budgetary Health Institution «Children’s Regional Hospital of the Kaliningrad Region», Kaliningrad, Russian Federation;
² Center of Immunology and Cellular Biotechnology, I. Kant Baltic Federal University,
Kaliningrad, Russian Federation;
³ Medical Institute of the Baltic Federal University. I. Kant, Kaliningrad, Russian Federation
Abstract. Allergic diseases (AD) are a widespread pathology. The largest proportion at AD is occupied by allergic rhinitis (24%), which in childhood is usually associated with enlargement of the adenoids and postnasal drip syndrome. In the examination of 3477 children with suspected AD, we included 1463 children aged more than 5 years in the SPC who had remission due to allergic pathology and no contraindications for examination. We detected reactions to household and epidermal allergens in 54% (n=675) and 38.3% (n=478) of the children, respectively. Diagnosis to plant aeroallergens revealed allergic sensitization to meadow and weed grasses in 55.5% (n=538) and 41.2% (n=399) of the children, respectively. According to the results of a comprehensive study with allergens, polyvalent hypersensitivity was found in 70.56% (n=441) of children. Thus, we found frequent polyvalent allergy sensitization by aeroallergens in children suffering from AD in Kaliningrad region.
Keywords: allergy sensitization, allergic diseases, allergic rhinitis, aeroallergens, household allergens, epidermal allergens, grass allergens, tree allergens
There is no conflict of interest.
Contact details of the corresponding author:
Evgeniya V. Davydova
davidova-ev.med@yandex.ru
Received 25.07.2022
For citation:
Markhaychuk A.Z., Vulf M.A., Khaziakhmatova O.G., Litvinova L.S., Goncharov A.G., Gorbunova A.Yu., Malyarov A.M. Structure of allergosensitization in children with allergopatologies in the Kaliningrad region. Vestn. Ural. Med. Akad. Nauki. = Journal of Ural Medical Academic Science. 2022, Vol. 19, no. 3, pp. 339–346. DOI: 10.22138/2500-0918-2022-19-3-339-346 (In Russ)
REFERENCES
1. Khaitov R.M., Pinegin B.V., Yarilin A.A. Immunology. Atlas. — M.: GEOTAR-Media; 2011. (in Russ)
2. Nikiforova G.N., Fedoskova T.G., Svistushkin V.M. Allergic rhinitis. Problems of patient management. Russian medical journal. 2018. No. 8(I): 46-52 (in Russ)
3. Balabolkin I.I. Actual problems of childhood allergology at the present stage. Pediatrics. 2012. 91(3): 69–75. (in Russ)
4. Clinical guidelines Allergic rhinitis in children. — M.: Union of Pediatricians of Russia, RAAKI; 2016. (in Russ)
5. Allergic rhinitis in children: guidelines and algorithm for pediatric allergic rhinitis. — M.: RADAR; 2015. (in Russ)
6. Khaitov M.R., Namazova-Baranova L.S., Ilyina N.I. ARIA 2019: Allergic Rhinitis Care Algorithms in Russia. Russian Allergological Journal. 2020. 17(1): 7-22. doi: 10.36691/RAJ.2020.17.1.001 (in Russ)
Authors
Ayshat Z. Markhaichuk
State Budgetary Health Institution «Children’s Regional Hospital of the Kaliningrad Region»
allergist-immunologist
Russian Federation, 236017, Kaliningrad, D.Donskoy st., 23
ayshat.90@rambler.ru
Maria A. Vulf
Center for Immunology and Cellular Biotechnologies of the IKBFU I. Kant.
Candidate of Biological Sciences, Senior Researcher
Russian Federation, 236041, Kaliningrad, st. Gaidara, 6
mary-jean@yandex.ru
Olga G. Khaziakhmatova
Center for Immunology and Cellular Biotechnologies of the IKBFU I. Kant.
Candidate of Biological Sciences, Senior Researcher
Russian Federation, 236041, Kaliningrad, st. Gaidara, 6
hazik36@mail.ru
Larisa S. Litvinova
Center for Immunology and Cellular Biotechnologies of the IKBFU I. Kant.
Doctor of Medical Sciences, Director
Russian Federation, 236041, Kaliningrad, st. Gaidara, 6
larisalitvinova@yandex.ru
Andrey G. Goncharov
Center for Immunology and Cellular Biotechnologies of the IKBFU I. Kant.
Candidate of Biological Sciences, Senior Researcher
Russian Federation, 236041, Kaliningrad, st. Gaidara, 6
agoncharov59@mail.ru
Alesya Yu. Gorbunova
Medical Institute of the IKBFU
resident
Russian Federation, 236041, Kaliningrad, st. Botkina, 4-6
Alexander M. Malyarov
State Budgetary Health Institution «Children’s Regional Hospital of the Kaliningrad Region»
Chief Physician
Russian Federation, 236017, Kaliningrad, D.Donskoy st., 23
dob@infomed39.ru