Ultramorfologic spetialities in the placenta at the powerless labour
Milyaeva N.M., Kovalev V.V., Tulakina L.G., Pichugova S.V.,
Klein A.V., Beykin Y.B.
Abstract. In recent years, numerous studies scientists are increasingly point to the importance of presence in the placenta of metabolic disturbances associated with lack of circulation, and in violation of the ultrastructure of cells in the architecture of gestational and birth defects.
Objective: To investigate the ultrastructural characteristics of the placenta to identify morphological criteria mitochondrial pathology at the powerless labor, using high-quality electron microscopic analysis.
Material and methods. At present, prospective study included 10 pregnant women aged 21–30 years (mean age 26.0±1.2 years): I group — five women whose labors proceeded with the weakness of labor activity; group II — coordinated labors. In this study, we conducted electron microscopic examination of the placenta with a weak state and coordinated labor. It has been studied 10 tests, viewed more than 200 sections. Presented to the demonstration 27 electron microscopic image.
Results of the study. Based on the studies and the data obtained the following conclusions: the weakness of labor occurs defeat the placenta at the ultrastructural level with the formation of degradation of cell architecture, including the pronounced changes in the cell nucleus. Those most exposed to the defeat of mitochondria in endothelial cells of blood vessels, sintitsiotrofoblaste, which leads to malnutrition fetoplacental complex. Decompensation placental complex in the weakness of labor is a consequence of dysfunction ultramorfostrukturnyh elements placental cells, microcirculation, metabolic syndrome and acute indications for emergency operative delivery.
Keywords: powerless labor, placenta, mitochondrial pathology, electron microscopy
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Authors:
Milyaeva Natalia M.
MD, assistant professor of obstetrics and gynecology FPC and PCB, Head OAPB maternity hospital №14 UIA GKB
soneta64@rambler.ru
Kovalev Vladislav V.
MD, Professor, Head of the Department of Obstetrics and Gynecology, FPC and PCB
vvkovalev55@gmail.ru
Ural State Medical University
Russian Federation, 620028, Yekaterinburg, ul. Repin, 3
Tulakina Lyudmila G.
MD, Head of the Laboratory of Electron Microscopy
ekb-lem@mail.ru
Pichugovа Svetlana V.
MD, a physician Laboratory of Electron Microscopy
ekb-lem@mail.ru
Klein Alex V.
MD, a physician Laboratory of Electron Microscopy
ekb-lem@mail.ru
Beykin Yakov B.
MD, professor, honored doctor of the Russian Federation, member of the Russian Academy of Sciences, chief physician UIA «Clinical and Diagnostic Center»
ekb-lem@mail.ru
MAU «Clinical and Diagnostic Center», Yekaterinburg
Russian Federation 620144, Yekaterinburg, Str. March 8, 78 V
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