Effect of Macrophage Activity Modulation on the Content of Leukocytes in Peripheral Blood and Bone Marrow of Rats with Alloxan Diabetes

Gette I.F., Bulavintseva T.S.

Institute of Immunology and physiology of the Ural Branch
of the Russian Academy of Sciences,
Yekaterinburg, Russian Federation

Abstract. Modulation of the macrophage activity in rats with alloxan diabetes caused a decrease of the total number of leukocytes and the lymphocyte fraction of peripheral blood as well as lymphocyte precursors in the bone marrow and was accompanied with correction of characteristic diabetic parameters — glucose, glycosylated hemoglobin and insulin.
Keywords: leukocytes, lymphocytes, macrophages, alloxan diabetes, immunomodulator

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Authors
Gette Irina F., i.goette@yandex.ru
Institute of Immunology and Physiology of the Ural Branch of the Russian Academy of Sciences
PhD, Senior Researcher
620049 Russian Federation, Yekaterinburg, Pervomajskaja, 106

Bulavintseva Tatiana S., omella@yandex.ru
Junior Researcher