Effect of Olygopeptide to Lipid Peroxidation and Antioxidant Activity in Peripheral Blood of Rats of Different Age under Immobilization Stress

Shcherbakov D. L., Meshchaninov V. N., 
Zharkov S. V.

GAUZ SO Center providing specialized types of medical care «Institute for Medical Cell Technologies»,
Ural State Medical University,
Yekaterinburg, Russian Federation

Abstract.

Immobilisation after 12 hours causes highly specific stress reaction in lipid peroxydation/antioxidant protection system. Antioxidant protective effect of neuropeptide dalargin was found in peripheral blood of adult animals. It`s influence realized by increasing activity of antioxidant enzymes, especially catalase, mostly in old animals.

Keywords:

metabolism, antioxidant, aging, peptides, lypoperoxidation, immobilization

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Authors
Shcherbakov Denis L. 
cdcom2@yandex.ru
Ural State Medical University, Russian Ministry of Health, 620028, st. Repina 3, Yekaterinburg, Russian Federation;
GAUZ SO Center providing specialized types of medical care «Institute for Medical Cell Technologies», Researcher of Anti-aging laboratory
620036, st. Soboleva 25, Yekaterinburg, Russian Federation
Meshchaninov Victor N. 
mv-02@yandex.ru
Ural State Medical University, Russian Ministry of Health, Head of biochemical department, Professor, MD, 620028, st. Repina 3, Yekaterinburg, Russian Federation.
GAUZ SO Center providing specialized types of medical care «Institute for Medical Cell Technologies», Head of Anti-aging laboratory
620036, st. Soboleva 25, Yekaterinburg, Russian Federation
Zharkov Sergey V. 
sergey_zharkov@list.ru
Ural State Medical University, Russian Ministry of Health
GAUZ SO Center providing specialized types of medical care «Institute for Medical Cell Technologies», Researcher of Anti-aging laboratory
620028, st. Repina 3, Yekaterinburg, Russian Federation.
620036, st. Soboleva 25, Yekaterinburg, Russian Federation