IDENTIFYING THE RISK OF COMPLICATIONS OF PERIPROSTHETIC INFECTION BASED ON ANTHROPOMETRIC DATA AND SURGICAL PARAMETERS
DOI: 10.22138/2500-0918-2025-22-1-6-16
A.I. Gajdyshev, E.L. Matveeva, A.G. Gasanova
Federal State Budgetary Institution "Scientific Research Center named after academician G. Ilizarova» Ministry of Health of the Russian Federation, Kurgan, Russian Federation
Abstract. During endoprosthesis operations, the occurrence of periprosthetic infection (PRI) remains an acute problem. Risk assessment of the development of PPI is extremely relevant for health facilities at all levels. The aim of the study was to evaluate the possibilities of predicting the development of periprosthetic infection based on anthropometric and clinical laboratory data of the patient, as well as some quantitative parameters of surgical intervention. Materials and methods. A retrospective analysis of case histories with a search depth of 13 years was carried out. The study included 65 men and 98 women; the average age of patients was 65=9 years. The patients were divided into 2 groups. The patients of the first group underwent primary endoprosthetics, and after the manifestation of the infection they were treated at the clinic of purulent osteology of the Federal State Budgetary Institution «NMIC TO named after Academician G.A. Ilizarov». In patients of the second group, no development of PPI was detected within 5 years after primary endoprosthesis. To assess the reliability of the results of the study, the Wilcoxon criterion, the χ-criterion, and the Puri-Sena-Tamura criterion were used.The prognostic significance of the parameters was assessed based on a comparison of the areas under the ROC curve. Significant parameters from the point of view of clinical significance were selected for the study: impaired carbohydrate metabolism, high body mass index, duration of surgery, large blood loss and hemotransfusion. Results. The average values of the parameters for non-binary samples and the fractions for binary ones are calculated. Using the Wilcoxon criterion and the χ-criterion, statistically significant differences were revealed between patients with a history of PPI and without it in the period 5 years after endoprosthesis.A multidimensional analysis using the Puri-Sena-Tamura criterion was carried out and differences between the groups were revealed. A logistic regression is constructed. Conclusion. The parameters influencing the occurrence of diabetes mellitus, hemotransfusion, and the volume of blood loss during surgery have been determined. Despite the small number of significant parameters, to assess the risk of manifestation of periprosthetic infection, the possibility of predicting the development of PPI, including through logistic regression, is shown.
Keywords: knee joint, periprosthetic infection, revision arthroplasty, anthropometry
There is no conflict of interest.
Contact details of the corresponding author:
Al'bert I. Gajdyshev
albert@ilizarov.ru
Received: 24.10.2024
For citation: Gajdyshev A.I., Matveeva E.L., Gasanova A.G. Identifying the risk of complications of periprosthetic infection based on anthropometric data and surgical parameters. [Online] Vestn. Ural. Med. Akad. Nauki. = Journal of Ural Medical Academic Science. 2025, Vol. 22, no. 1, pp. 6—16. DOI: 10.22138/2500-0918-2025-22-1-6-16 (In Russ)
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Authors
Al'bert I. Gajdyshev
Candidate of Biological Sciences, Head of the Department of Information Technology and Information Security
albert@ilizarov.ru
Elena L. Matveeva
Doctor of Biological Sciences, Senior researcher at the Department of Preclinical and Laboratory Research
matveevan@mail.ru
Anna G. Gasanova
Senior Researcher at the Department of Preclinical and Laboratory Research.
gasanova.08@mail.ru
Federal State Budgetary Institution "Scientific Research Center named after academician G. Ilizarova» Ministry of Health of the Russian Federation
Kurgan, Russian Federetion