Nanoparticle’s interactions with biological objects (The review)
DOI: 10.22138/2500-0918-2016-15-3-97-111
A.P. Sarapultsev, S.V. Rempel, Ju.V. Kuznetsova, G.P. Sarapultsev
Institute of Immunology and Physiology of the Ural Branch of the Russian Academy of Sciences,Yekaterinburg, Russian Federation;
Ural Federal University named after the first President of Russia B.N. Yeltsin, Yekaterinburg, Russian Federation;
Institute of Solid State Chemistry of the Ural Branch of the Russian Academy of Sciences, Yekaterinburg, Russian Federation
Abstract.
This review covers main aspects of the structure and properties of nanoparticles, defining peculiarities of their interaction with biological objects. Special attention is paid to the mechanisms of energy-using endocytosis (clathrin-mediated endocytosis, caveolae, macropinocytosis, and phagocytosis). The basic parameters of nanoparticles affecting their biological (toxic) action are described.
Keywords:
nanomaterials, quantum dots, nanoparticles, biology, toxicology, membranes, medicine, endocyt
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Authors
Sarapultsev Alexey P.
Institute of Immunology and Physiology
PhD, MD Senior researcher
620049,106, Pervomayskaya str., Yekaterinburg, Russian Federation
a.sarapultsev@gmail.com
Rempel Svetlana V.
Institute of Solid State Chemistry of the Ural Branch of the Russian Academy of Sciences
620990, 91, Pervomayskaya str., Yekaterinburg, Russian Federation
Associate professor
Svetlana_rempel@ihim.uran.ru
Kuznetsova Julia V.
Institute of Solid State Chemistry of the Ural Branch of the Russian Academy of Sciences
620990, 91, Pervomayskaya street, Yekaterinburg, Russian Federation
postgraduate
jukuznetsova@mail.ru
Sarapultsev German P.
Institute of Immunology and Physiology
620049,106, Pervomayskaya street, Yekaterinburg, Russian Federation
junior researcher
dr.sarapultsev@gmail.com
Received — 04.03.16
For citation: Sarapultsev A.P., Rempel S.V., Kuznetsova Ju.V., Sarapultsev G.P. Vzaimodejstvie nanochastic s biologicheskimi ob'ektami (obzor) [Nanoparticle’s interactions with biological objects (The Review)]. Vestn. Ural. Med. Akad. Nauki. – Journal of Ural Medical Academic Science. 2016, no. 3, pp. 97–111. DOI: 10.22138/2500-0918-2016-15-3-97-111[In Russ.]
